Gene: KIF2A

Alternate names for this Gene: CDCBM3|HK2|KIF2

Gene Summary: The protein encoded by this gene is a plus end-directed motor required for normal mitotic progression. The encoded protein is required for normal spindle activity during mitosis and is necessary for normal brain development. Several transcript variants encoding different isoforms have been found for this gene.

Gene is located in Chromosome: 5

Location in Chromosome : 5q12.1

Description of this Gene: kinesin family member 2A

Type of Gene: protein-coding

Gene: DIMT1

Alternate names for this Gene: DIM1|DIMT1L|HSA9761|HUSSY5

Gene Summary: The protein encoded by this gene is a methyltransferase that is responsible for dimethylation of adjacent adenosines near the 18S rRNA decoding site. The encoded protein is essential for ribosome biogenesis, although its catalytic activity is not involved in the process. The yeast ortholog of this protein functions in the cytoplasm while this protein functions in the nucleus.

Gene is located in Chromosome: 5

Location in Chromosome : 5q12.1

Description of this Gene: DIMT1 rRNA methyltransferase and ribosome maturation factor

Type of Gene: protein-coding

rs185048 in KIF2A;DIMT1 gene and Leukemia, Myelocytic, Acute PMID 27903959 2017 Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.