Gene: KLF10

Alternate names for this Gene: EGR-alpha|EGRA|TIEG|TIEG1

Gene Summary: This gene encodes a member of a family of proteins that feature C2H2-type zinc finger domains. The encoded protein is a transcriptional repressor that acts as an effector of transforming growth factor beta signaling. Activity of this protein may inhibit the growth of cancers, particularly pancreatic cancer. Alternative splicing results in multiple transcript variants.

Gene is located in Chromosome: 8

Location in Chromosome : 8q22.3

Description of this Gene: Kruppel like factor 10

Type of Gene: protein-coding

rs1050969 in KLF10 gene and Body Height PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.