Gene: KLK10

Alternate names for this Gene: NES1|PRSSL1

Gene Summary: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.

Gene is located in Chromosome: 19

Location in Chromosome : 19q13.41

Description of this Gene: kallikrein related peptidase 10

Type of Gene: protein-coding

rs2569454 in KLK10 gene and Blood Protein Measurement PMID 30072576 2018 Co-regulatory networks of human serum proteins link genetics to disease.