Gene: LGALS3

Alternate names for this Gene: CBP35|GAL3|GALBP|GALIG|L31|LGALS2|MAC2

Gene Summary: This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.

Gene is located in Chromosome: 14

Location in Chromosome : 14q22.3

Description of this Gene: galectin 3

Type of Gene: protein-coding