Gene: LINC02456

Alternate names for this Gene:

Gene Summary:

Gene is located in Chromosome:

Location in Chromosome :

Description of this Gene:

Type of Gene:

Gene: IGF1

Alternate names for this Gene: IGF|IGF-I|IGFI|MGF

Gene Summary: The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein.

Gene is located in Chromosome: 12

Location in Chromosome : 12q23.2

Description of this Gene: insulin like growth factor 1

Type of Gene: protein-coding

rs5742692 in LINC02456;IGF1 gene and Body Height PMID 20189936 2010 A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci.

rs5742692 in LINC02456;IGF1 gene and Height PMID 20189936 2010 A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci.

rs5742626 in LINC02456;IGF1 gene and High density lipoprotein measurement PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.

rs587779350 in LINC02456;IGF1 gene and Insulin-Like Growth Factor I Deficiency PMID 24389050 2014 Genomic analysis of primordial dwarfism reveals novel disease genes.

rs5742626 in LINC02456;IGF1 gene and Serum HDL cholesterol measurement PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.

rs5742643 in LINC02456;IGF1 gene and Systolic Pressure PMID 30224653 2018 Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.

rs5742626 in LINC02456;IGF1 gene and Triglycerides measurement PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.

rs9308315 in LINC02456;IGF1 gene and Vital capacity PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.