Gene: LMAN2L

Alternate names for this Gene: MRT52|VIPL

Gene Summary: This gene encodes a protein belonging to the L-type lectin group of type 1 membrane proteins, which function in the mammalian early secretory pathway. These proteins contain luminal carbohydrate recognition domains, which display homology to leguminous lectins. Unlike other proteins of the group, which cycle in the early secretory pathway and are predominantly associated with post endoplasmic reticulum membranes, the protein encoded by this gene is a non-cycling resident protein of the ER, where it functions as a cargo receptor for glycoproteins. It is proposed to regulate exchange of folded proteins for transport to the Golgi and exchange of misfolded glycoproteins for transport to the ubiquitin-proteasome pathway.

Gene is located in Chromosome: 2

Location in Chromosome : 2q11.2

Description of this Gene: lectin, mannose binding 2 like

Type of Gene: protein-coding