Gene: LOC105372632

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Gene: SLC12A5

Alternate names for this Gene: DEE34|EIEE34|EIG14|KCC2|hKCC2

Gene Summary: K-Cl cotransporters are proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The protein encoded by this gene is an integral membrane K-Cl cotransporter that can function in either a net efflux or influx pathway, depending on the chemical concentration gradients of potassium and chloride. The encoded protein can act as a homomultimer, or as a heteromultimer with other K-Cl cotransporters, to maintain chloride homeostasis in neurons. Alternative splicing results in two transcript variants encoding different isoforms.

Gene is located in Chromosome: 20

Location in Chromosome : 20q13.12

Description of this Gene: solute carrier family 12 member 5

Type of Gene: protein-coding

Gene: SLC12A5-AS1

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rs10432735 in LOC105372632;SLC12A5;SLC12A5-AS1 gene and Serum albumin measurement PMID 22286219 2012 Genome-wide association study identifies multiple loci influencing human serum metabolite levels.