Gene: LOC105375567

Alternate names for this Gene:

Gene Summary:

Gene is located in Chromosome:

Location in Chromosome :

Description of this Gene:

Type of Gene:

Gene: AOC1

Alternate names for this Gene: ABP|ABP1|DAO|DAO1|KAO

Gene Summary: This gene encodes a metal-binding membrane glycoprotein that oxidatively deaminates putrescine, histamine, and related compounds. The encoded protein is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene is located in Chromosome: 7

Location in Chromosome : 7q36.1

Description of this Gene: amine oxidase copper containing 1

Type of Gene: protein-coding

rs10452848 in LOC105375567;AOC1 gene and Blood Protein Measurement PMID 30072576 2018 Co-regulatory networks of human serum proteins link genetics to disease.

rs6977416 in LOC105375567;AOC1 gene and Body Height PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs6977081 in LOC105375567;AOC1 gene and Carpal Tunnel Syndrome PMID 30833571 2019 A genome-wide association analysis identifies 16 novel susceptibility loci for carpal tunnel syndrome.

rs17173637 in LOC105375567;AOC1 gene and High density lipoprotein measurement PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.

PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.

PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.

rs17173637 in LOC105375567;AOC1 gene and Serum HDL cholesterol measurement PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.

rs6977416 in LOC105375567;AOC1 gene and Vital capacity PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.