Gene: LOC105377730

Alternate names for this Gene:

Gene Summary:

Gene is located in Chromosome:

Location in Chromosome :

Description of this Gene:

Type of Gene:

Gene: DUSP1

Alternate names for this Gene: CL100|HVH1|MKP-1|MKP1|PTPN10

Gene Summary: The protein encoded by this gene is a phosphatase with dual specificity for tyrosine and threonine. The encoded protein can dephosphorylate MAP kinase MAPK1/ERK2, which results in its involvement in several cellular processes. This protein appears to play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation. Finally, the encoded protein can make some solid tumors resistant to both chemotherapy and radiotherapy, making it a target for cancer therapy.

Gene is located in Chromosome: 5

Location in Chromosome : 5q35.1

Description of this Gene: dual specificity phosphatase 1

Type of Gene: protein-coding