Gene: LOC105377986

Alternate names for this Gene:

Gene Summary:

Gene is located in Chromosome:

Location in Chromosome :

Description of this Gene:

Type of Gene:

Gene: HEY2

Alternate names for this Gene: CHF1|GRIDLOCK|GRL|HERP1|HESR2|HRT2|bHLHb32

Gene Summary: This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. The encoded protein forms homo- or hetero-dimers that localize to the nucleus and interact with a histone deacetylase complex to repress transcription. Expression of this gene is induced by the Notch signal transduction pathway. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternatively spliced transcript variants have been found, but their biological validity has not been determined.

Gene is located in Chromosome: 6

Location in Chromosome : 6q22.31

Description of this Gene: hes related family bHLH transcription factor with YRPW motif 2

Type of Gene: protein-coding

rs3966775 in LOC105377986;HEY2 gene and Body Height PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.