Gene: LRRC2

Alternate names for this Gene: -

Gene Summary: This gene encodes a member of the leucine-rich repeat-containing family of proteins, which function in diverse biological pathways. This family member may possibly be a nuclear protein. Similarity to the RAS suppressor protein, as well as expression down-regulation observed in tumor cells, suggests that it may function as a tumor suppressor. The gene is located in the chromosome 3 common eliminated region 1 (C3CER1), a 1.4 Mb region that is commonly deleted in diverse tumors. A related pseudogene has been identified on chromosome 2.

Gene is located in Chromosome: 3

Location in Chromosome : 3p21.31

Description of this Gene: leucine rich repeat containing 2

Type of Gene: protein-coding

Gene: TDGF1

Alternate names for this Gene: CR|CR-1|CRGF|CRIPTO

Gene Summary: This gene encodes an epidermal growth factor-related protein that contains a cripto, FRL-1, and cryptic domain. The encoded protein is an extracellular, membrane-bound signaling protein that plays an essential role in embryonic development and tumor growth. Mutations in this gene are associated with forebrain defects. Pseudogenes of this gene are found on chromosomes 2, 3, 6, 8, 19 and X. Alternate splicing results in multiple transcript variants.

Gene is located in Chromosome: 3

Location in Chromosome : 3p21.31

Description of this Gene: teratocarcinoma-derived growth factor 1

Type of Gene: protein-coding