Gene: MAF1

Alternate names for this Gene: -

Gene Summary: This gene encodes a protein that is similar to Maf1, a Saccharomyces cerevisiae protein highly conserved in eukaryotic cells. Yeast Maf1 is a negative effector of RNA polymerase III (Pol III). It responds to changes in the cellular environment and represses pol III transcription. Biochemical studies identified the initiation factor TFIIIB as a target for Maf1-dependent repression.

Gene is located in Chromosome: 8

Location in Chromosome : 8q24.3

Description of this Gene: MAF1 homolog, negative regulator of RNA polymerase III

Type of Gene: protein-coding

Gene: SHARPIN

Alternate names for this Gene: SIPL1

Gene Summary:

Gene is located in Chromosome: 8

Location in Chromosome : 8q24.3

Description of this Gene: SHANK associated RH domain interactor

Type of Gene: protein-coding

rs34173062 in MAF1;SHARPIN gene and Blood basophil count (lab test) PMID 27863252 2016 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.

rs34173062 in MAF1;SHARPIN gene and Eosinophil count procedure PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

PMID 27863252 2016 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.

rs34173062 in MAF1;SHARPIN gene and Respiratory Tract Diseases PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.