Gene: MBL2
Alternate names for this Gene: COLEC1|HSMBPC|MBL|MBL2D|MBP|MBP-C|MBP1|MBPD
Gene Summary: This gene encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes and binds to mannose and N-acetylglucosamine on many microorganisms, including bacteria, yeast, and viruses including influenza virus, HIV and SARS-CoV. This binding activates the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases.
Gene is located in Chromosome: 10
Location in Chromosome : 10q21.1
Description of this Gene: mannose binding lectin 2
Type of Gene: protein-coding