Gene: MBOAT1

Alternate names for this Gene: LPEAT1|LPLAT|LPLAT 1|LPSAT|OACT1|dJ434O11.1

Gene Summary: This gene belongs to the membrane-bound O-acetyltransferase superfamily. The encoded transmembrane protein is an enzyme that transfers organic compounds, preferably from oleoyl-CoA, to hydroxyl groups of protein targets in membranes. A translocation disrupting this gene may be associated with brachydactyly syndactyly syndrome. Alternately spliced transcript variants have been described for this gene.

Gene is located in Chromosome: 6

Location in Chromosome : 6p22.3

Description of this Gene: membrane bound O-acyltransferase domain containing 1

Type of Gene: protein-coding

rs2457333 in MBOAT1 gene and Body Height PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs10946364 in MBOAT1 gene and response to ACE inhibitor PMID 28030426 2017 Meta-analysis of genome-wide association studies on the intolerance of angiotensin-converting enzyme inhibitors.