Gene: MCM9

Alternate names for this Gene: C6orf61|MCMDC1|ODG4|dJ329L24.1|dJ329L24.3

Gene Summary: The protein encoded by this gene is a member of the mini-chromosome maintenance (MCM) protein family that are essential for the initiation of eukaryotic genome replication. Binding of this protein to chromatin has been shown to be a pre-requisite for recruiting the MCM2-7 helicase to DNA replication origins. This protein also binds, and is a positive regulator of, the chromatin licensing and DNA replication factor 1, CDT1.

Gene is located in Chromosome: 6

Location in Chromosome : 6q22.31

Description of this Gene: minichromosome maintenance 9 homologous recombination repair factor

Type of Gene: protein-coding

rs36139342 in MCM9 gene and Dehydroepiandrosterone sulfate measurement (procedure) PMID 31169883 2019 Genetic Association Study of Eight Steroid Hormones and Implications for Sexual Dimorphism of Coronary Artery Disease.

rs141980369 in MCM9 gene and Major Depressive Disorder PMID 30219690 2019 GWAS and systems biology analysis of depressive symptoms among smokers from the COPDGene cohort.

rs150141688 in MCM9 gene and Red Blood Cell Count measurement PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs141980369 in MCM9 gene and Smoking PMID 30219690 2019 GWAS and systems biology analysis of depressive symptoms among smokers from the COPDGene cohort.

rs9374757 in MCM9 gene and mathematical ability PMID 30038396 2018 Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.