Gene: MGST3

Alternate names for this Gene: GST-III

Gene Summary: This gene encodes a member of the MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) protein family. Members of this family are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. This gene encodes an enzyme which catalyzes the conjugation of leukotriene A4 and reduced glutathione to produce leukotriene C4. This enzyme also demonstrates glutathione-dependent peroxidase activity towards lipid hydroperoxides.

Gene is located in Chromosome: 1

Location in Chromosome : 1q24.1

Description of this Gene: microsomal glutathione S-transferase 3

Type of Gene: protein-coding

rs10737515 in MGST3 gene and Body Height PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.