Gene: MOB3B

Alternate names for this Gene: C9orf35|MOB1D|MOBKL2B

Gene Summary: The protein encoded by this gene shares similarity with the yeast Mob1 protein. Yeast Mob1 binds Mps1p, a protein kinase essential for spindle pole body duplication and mitotic checkpoint regulation. This gene is located on the opposite strand as the interferon kappa precursor (IFNK) gene.

Gene is located in Chromosome: 9

Location in Chromosome : 9p21.2

Description of this Gene: MOB kinase activator 3B

Type of Gene: protein-coding

rs10511816 in MOB3B gene and Amyotrophic Lateral Sclerosis PMID 23587638 2013 Residual association at C9orf72 suggests an alternative amyotrophic lateral sclerosis-causing hexanucleotide repeat.

PMID 20801718 2010 Chromosome 9p21 in amyotrophic lateral sclerosis in Finland: a genome-wide association study.

PMID 25442119 2015 Second-generation Irish genome-wide association study for amyotrophic lateral sclerosis.

rs10967921 in MOB3B gene and Body Height PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs17779457 in MOB3B gene and Lower Urinary Tract Symptoms PMID 23376709 2013 A 2-stage genome-wide association study to identify single nucleotide polymorphisms associated with development of urinary symptoms after radiotherapy for prostate cancer.

rs17779457 in MOB3B gene and Prostate carcinoma PMID 23376709 2013 A 2-stage genome-wide association study to identify single nucleotide polymorphisms associated with development of urinary symptoms after radiotherapy for prostate cancer.