Gene: MROH6

Alternate names for this Gene: C8orf73

Gene Summary:

Gene is located in Chromosome: 8

Location in Chromosome : 8q24.3

Description of this Gene: maestro heat like repeat family member 6

Type of Gene: protein-coding

rs11352430 in MROH6 gene and Drug-induced neutropenia PMID 28762467 2018 Sulfasalazine-Induced Agranulocytosis Is Associated With the Human Leukocyte Antigen Locus.

rs10866912 in MROH6 gene and Schizophrenia PMID 31268507 2019 Given this gene's role in niacin metabolism and the evidence for niacin deficiency provoking schizophrenialike symptoms in neuropsychiatric diseases such as pellagra and Hartnup disease, these results suggest that the rs10866912 genotype and niacin status may have implications for schizophrenia susceptibility and treatment.

PMID 31268507 2019 Association of Schizophrenia Risk With Disordered Niacin Metabolism in an Indian Genome-wide Association Study.