Gene: NBL1

Alternate names for this Gene: D1S1733E|DAN|DAND1|NB|NO3

Gene Summary: This gene product is the founding member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. These proteins are secreted, and act as BMP (bone morphogenetic protein) antagonists by binding to BMPs and preventing them from interacting with their receptors. They may thus play an important role during growth and development. Alternatively spliced transcript variants have been identified for this gene. Read-through transcripts between this locus and the upstream mitochondrial inner membrane organizing system 1 gene (GeneID 440574) have been observed.

Gene is located in Chromosome: 1

Location in Chromosome : 1p36.13

Description of this Gene: NBL1, DAN family BMP antagonist

Type of Gene: protein-coding

Gene: MICOS10-NBL1

Alternate names for this Gene: C1orf151-NBL1|DAN|DAND1|MINOS1-NBL1|NBL1

Gene Summary: This locus represents naturally occurring read-through transcription between the neighboring chromosome 1 open reading frame 151 (GeneID 440574) and neuroblastoma suppressor of tumorigenicity 1 (GeneID 4681) genes on chromosome 1. The read-through transcripts produce at least two proteins, each of which share identity with proteins translated from the downstream neuroblastoma suppressor of tumorigenicity 1 locus.

Gene is located in Chromosome: 1

Location in Chromosome : 1p36.13

Description of this Gene: MICOS10-NBL1 readthrough

Type of Gene: protein-coding