Gene: NDRG2

Alternate names for this Gene: SYLD

Gene Summary: This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein that may play a role in neurite outgrowth. This gene may be involved in glioblastoma carcinogenesis. Alternative splicing results in multiple transcript variants.

Gene is located in Chromosome: 14

Location in Chromosome : 14q11.2

Description of this Gene: NDRG family member 2

Type of Gene: protein-coding

Gene: ARHGEF40

Alternate names for this Gene: SOLO

Gene Summary: This gene encodes a protein similar to guanosine nucleotide exchange factors for Rho GTPases. The encoded protein contains in its C-terminus a GEF domain involved in exchange activity and a pleckstrin homology domain. Alternatively spliced transcripts that encode different proteins have been described.

Gene is located in Chromosome: 14

Location in Chromosome : 14q11.2

Description of this Gene: Rho guanine nucleotide exchange factor 40

Type of Gene: protein-coding

rs8019890 in NDRG2;ARHGEF40 gene and Body Height PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.