Gene: NHEJ1
Alternate names for this Gene: XLF
Gene Summary: Double-strand breaks in DNA result from genotoxic stresses and are among the most damaging of DNA lesions. This gene encodes a DNA repair factor essential for the nonhomologous end-joining pathway, which preferentially mediates repair of double-stranded breaks. Mutations in this gene cause different kinds of severe combined immunodeficiency disorders.
Gene is located in Chromosome: 2
Location in Chromosome : 2q35
Description of this Gene: non-homologous end joining factor 1
Type of Gene: protein-coding
rs16859517 in
NHEJ1 gene and
Body Height
PMID 25282103 2014 Defining the role of common variation in the genomic and biological architecture of adult human height.
PMID 18391952 2008 Genome-wide association analysis identifies 20 loci that influence adult height.
PMID 25429064 2015 Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci.
PMID 31562340 2019 Characterizing rare and low-frequency height-associated variants in the Japanese population.
rs6724465 in
NHEJ1 gene and
Height
PMID 18391952 2008 Genome-wide association analysis identifies 20 loci that influence adult height.