Gene: NKAPL

Alternate names for this Gene:

Gene Summary:

Gene is located in Chromosome:

Location in Chromosome :

Description of this Gene:

Type of Gene:

Gene: ZKSCAN4

Alternate names for this Gene: P1P373C6|ZNF307|ZNF427|ZSCAN36

Gene Summary:

Gene is located in Chromosome: 6

Location in Chromosome : 6p22.1

Description of this Gene: zinc finger with KRAB and SCAN domains 4

Type of Gene: protein-coding

rs12000 in NKAPL;ZKSCAN4 gene and Rheumatoid Arthritis PMID 19503088 2009 REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis.

rs1635 in NKAPL;ZKSCAN4 gene and Schizophrenia PMID 22037552 2011 We identified two susceptibility loci for schizophrenia at 6p21-p22.1 (rs1233710 in an intron of ZKSCAN4, P(combined) = 4.76 × 10(-11), odds ratio (OR) = 0.79; rs1635 in an exon of NKAPL, P(combined) = 6.91 × 10(-12), OR = 0.78; rs2142731 in an intron of PGBD1, P(combined) = 5.14 × 10(-10), OR = 0.79) and 11p11.2 (rs11038167 near the 5' UTR of TSPAN18, P(combined) = 1.09 × 10(-11), OR = 1.29; rs11038172, P(combined) = 7.21 × 10(-10), OR = 1.25; rs835784, P(combined) = 2.73 × 10(-11), OR = 1.27).