Gene: NLGN4X

Alternate names for this Gene: ASPGX2|AUTSX2|HLNX|HNL4X|NLGN4

Gene Summary: This gene encodes a member of the type-B carboxylesterase/lipase protein family. The encoded protein belongs to a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. The encoded protein interacts with discs large homolog 4 (DLG4). Mutations in this gene have been associated with autism and Asperger syndrome. Alternative splicing results in multiple transcript variants.

Gene is located in Chromosome: X

Location in Chromosome : Xp22.32-p22.31

Description of this Gene: neuroligin 4 X-linked

Type of Gene: protein-coding