Gene: NLRP9

Alternate names for this Gene: CLR19.1|NALP9|NOD6|PAN12

Gene Summary: The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). This protein may play a regulatory role in the innate immune system as similar family members belong to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5.

Gene is located in Chromosome: 19

Location in Chromosome : 19q13.42

Description of this Gene: NLR family pyrin domain containing 9

Type of Gene: protein-coding

rs58869521 in NLRP9 gene and Body Height PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.