Gene: NME1-NME2

Alternate names for this Gene: NM23-LV|NMELV

Gene Summary: This locus represents naturally occurring read-through transcription between the neighboring NME1 and NME2 genes. The significance of this read-through transcription and the function of the resulting protein product have not yet been determined. Alternative splicing of this gene results in multiple transcript variants.

Gene is located in Chromosome: 17

Location in Chromosome : 17q21.33

Description of this Gene: NME1-NME2 readthrough

Type of Gene: protein-coding

Gene: NME2

Alternate names for this Gene: NDKB|NDPK-B|NDPKB|NM23-H2|NM23B|PUF

Gene Summary: Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by NME1) and 'B' (encoded by this gene) isoforms. Multiple alternatively spliced transcript variants have been found for this gene. Read-through transcription from the neighboring upstream gene (NME1) generates naturally-occurring transcripts (NME1-NME2) that encode a fusion protein comprised of sequence sharing identity with each individual gene product.

Gene is located in Chromosome: 17

Location in Chromosome : 17q21.33

Description of this Gene: NME/NM23 nucleoside diphosphate kinase 2

Type of Gene: protein-coding

rs4605213 in NME1-NME2;NME2 gene and Body Height PMID 20881960 2010 Hundreds of variants clustered in genomic loci and biological pathways affect human height.

PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs4605213 in NME1-NME2;NME2 gene and Height PMID 20881960 2010 Hundreds of variants clustered in genomic loci and biological pathways affect human height.