Gene: NOSTRIN

Alternate names for this Gene: DaIP2

Gene Summary: Nitric oxide (NO) is a potent mediator in biologic processes such as neurotransmission, inflammatory response, and vascular homeostasis. NOSTRIN binds the enzyme responsible for NO production, endothelial NO synthase (ENOS; MIM 163729), and triggers the translocation of ENOS from the plasma membrane to vesicle-like subcellular structures, thereby attenuating ENOS-dependent NO production.[supplied by OMIM, Apr 2004].

Gene is located in Chromosome: 2

Location in Chromosome : 2q24.3

Description of this Gene: nitric oxide synthase trafficking

Type of Gene: protein-coding

Gene: SPC25

Alternate names for this Gene: AD024|SPBC25|hSpc25

Gene Summary: This gene encodes a protein that may be involved in kinetochore-microtubule interaction and spindle checkpoint activity.

Gene is located in Chromosome: 2

Location in Chromosome : 2q24.3

Description of this Gene: SPC25 component of NDC80 kinetochore complex

Type of Gene: protein-coding

rs540652 in NOSTRIN;SPC25 gene and Body Height PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs3931 in NOSTRIN;SPC25 gene and Monocyte count procedure PMID 27863252 2016 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.

rs3931 in NOSTRIN;SPC25 gene and Monocyte count result PMID 27863252 2016 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.

rs488621 in NOSTRIN;SPC25 gene and White Blood Cell Count procedure PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.