Gene: NRROS

Alternate names for this Gene: ELLP3030|GARPL1|LRRC33|SENEBAC|UNQ3030

Gene Summary:

Gene is located in Chromosome: 3

Location in Chromosome : 3q29

Description of this Gene: negative regulator of reactive oxygen species

Type of Gene: protein-coding

Gene: PIGX

Alternate names for this Gene: PIG-X

Gene Summary: This gene encodes a type I transmembrane protein in the endoplasmic reticulum (ER). The protein is an essential component of glycosylphosphatidylinositol-mannosyltransferase I, which transfers the first of the four mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Studies in rat indicate that the protein is translated from a non-AUG translation initiation site. Alternative splicing results in multiple transcript variants.

Gene is located in Chromosome: 3

Location in Chromosome : 3q29

Description of this Gene: phosphatidylinositol glycan anchor biosynthesis class X

Type of Gene: protein-coding

rs80064395 in NRROS;PIGX gene and Allergic Reaction PMID 29083406 2017 Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.

rs12152276 in NRROS;PIGX gene and Eczema PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs11185551 in NRROS;PIGX gene and Eosinophil count procedure PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.