Gene: OSBP2

Alternate names for this Gene: HLM|ORP-4|ORP4|OSBPL1|OSBPL4

Gene Summary: The protein encoded by this gene contains a pleckstrin homology (PH) domain and an oxysterol-binding region. It binds oxysterols such as 7-ketocholesterol and may inhibit their cytotoxicity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene is located in Chromosome: 22

Location in Chromosome : 22q12.2

Description of this Gene: oxysterol binding protein 2

Type of Gene: protein-coding

rs136237 in OSBP2 gene and Glomerular Filtration Rate PMID 30920136 2019 The impact of donor and recipient common clinical and genetic variation on estimated glomerular filtration rate in a European renal transplant population.

rs35396069 in OSBP2 gene and High density lipoprotein measurement PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.

rs7290980 in OSBP2 gene and RDW - Red blood cell distribution width result PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs7290980 in OSBP2 gene and Red cell distribution width determination PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs35396069 in OSBP2 gene and Serum HDL cholesterol measurement PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.

rs136293 in OSBP2 gene and mathematical ability PMID 30038396 2018 Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.