Gene: P2RY14

Alternate names for this Gene: BPR105|GPR105|P2Y14

Gene Summary: The product of this gene belongs to the family of G-protein coupled receptors, which contains several receptor subtypes with different pharmacological selectivity for various adenosine and uridine nucleotides. This receptor is a P2Y purinergic receptor for UDP-glucose and other UDP-sugars coupled to G-proteins. It has been implicated in extending the known immune system functions of P2Y receptors by participating in the regulation of the stem cell compartment, and it may also play a role in neuroimmune function. Two transcript variants encoding the same protein have been identified for this gene.

Gene is located in Chromosome: 3

Location in Chromosome : 3q25.1

Description of this Gene: purinergic receptor P2Y14

Type of Gene: protein-coding

Gene: MED12L

Alternate names for this Gene: NIZIDS|NOPAR|TNRC11L|TRALP|TRALPUSH

Gene Summary: The protein encoded by this gene is part of the Mediator complex, which is involved in transcriptional coactivation of nearly all RNA polymerase II-dependent genes. The Mediator complex links gene-specific transcriptional activators with the basal transcription machinery.

Gene is located in Chromosome: 3

Location in Chromosome : 3q25.1

Description of this Gene: mediator complex subunit 12L

Type of Gene: protein-coding

rs4680250 in P2RY14;MED12L gene and Eosinophil count procedure PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.