Gene: P4HTM

Alternate names for this Gene: EGLN4|HIDEA|HIFPH4|P4H-TM|PH-4|PH4|PHD4

Gene Summary: The product of this gene belongs to the family of prolyl 4-hydroxylases. This protein is a prolyl hydroxylase that may be involved in the degradation of hypoxia-inducible transcription factors under normoxia. It plays a role in adaptation to hypoxia and may be related to cellular oxygen sensing. Alternatively spliced variants encoding different isoforms have been identified.

Gene is located in Chromosome: 3

Location in Chromosome : 3p21.31|3p21.3

Description of this Gene: prolyl 4-hydroxylase, transmembrane

Type of Gene: protein-coding

rs6446204 in P4HTM gene and Waist-Hip Ratio PMID 30575882 2018 Association of Genetic Variants Related to Gluteofemoral vs Abdominal Fat Distribution With Type 2 Diabetes, Coronary Disease, and Cardiovascular Risk Factors.