Gene: PABPC1

Alternate names for this Gene: PAB1|PABP|PABP1|PABPC2|PABPL1

Gene Summary: This gene encodes a poly(A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation; it is also required for poly(A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes.

Gene is located in Chromosome: 8

Location in Chromosome : 8q22.3

Description of this Gene: poly(A) binding protein cytoplasmic 1

Type of Gene: protein-coding