Gene: PDK2

Alternate names for this Gene: PDHK2|PDKII

Gene Summary: This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene is located in Chromosome: 17

Location in Chromosome : 17q21.33

Description of this Gene: pyruvate dehydrogenase kinase 2

Type of Gene: protein-coding