Gene: PIGF

Alternate names for this Gene: -

Gene Summary: This gene encodes a protein involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor, a glycolipid containing three mannose molecules in its core backbone, is found on many blood cells where it serves to anchor proteins to the cell surface. The encoded protein and another GPI synthesis protein, PIGO, function in the transfer of ethanolaminephosphate to the third mannose in GPI. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene is located in Chromosome: 2

Location in Chromosome : 2p21

Description of this Gene: phosphatidylinositol glycan anchor biosynthesis class F

Type of Gene: protein-coding

rs17818399 in PIGF gene and Body Height PMID 20966902 2011 Genome-wide association study of anthropometric traits and evidence of interactions with age and study year in Filipino women.

rs17818399 in PIGF gene and Height PMID 20966902 2011 Genome-wide association study of anthropometric traits and evidence of interactions with age and study year in Filipino women.

rs13000706 in PIGF gene and Lymphocyte Count measurement PMID 22286170 2012 The combination of a genome-wide association study of lymphocyte count and analysis of gene expression data reveals novel asthma candidate genes.