Gene: PLPPR1

Alternate names for this Gene: LPPR1|PRG-3

Gene Summary: This gene encodes a member of the plasticity-related gene (PRG) family. Members of the PRG family mediate lipid phosphate phosphatase activity in neurons and are known to be involved in neuronal plasticity. The protein encoded by this gene does not perform its function through enzymatic phospholipid degradation. This gene is strongly expressed in brain. It shows dynamic expression regulation during brain development and neuronal excitation. Alternatively spliced transcript variants encoding the same protein have been observed.

Gene is located in Chromosome: 9

Location in Chromosome : 9q31.1

Description of this Gene: phospholipid phosphatase related 1

Type of Gene: protein-coding

rs7026834 in PLPPR1 gene and Body Height PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs73656147 in PLPPR1 gene and Parkinson Disease PMID 30338293 2018 Plasticity-related gene 3 (LPPR1) and age at diagnosis of Parkinson disease.