Gene: POU3F2

Alternate names for this Gene: BRN2|N-Oct3|OCT7|OTF-7|OTF7|POUF3|brn-2|oct-7

Gene Summary: This gene encodes a member of the POU-III class of neural transcription factors. The encoded protein is involved in neuronal differentiation and enhances the activation of corticotropin-releasing hormone regulated genes. Overexpression of this protein is associated with an increase in the proliferation of melanoma cells.

Gene is located in Chromosome: 6

Location in Chromosome : 6q16.1

Description of this Gene: POU class 3 homeobox 2

Type of Gene: protein-coding

rs3823036 in POU3F2 gene and Intelligence PMID 29942086 2018 Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.

PMID 29844566 2018 Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.

rs3823036 in POU3F2 gene and mathematical ability PMID 30038396 2018 Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.