Gene: PPM1B

Alternate names for this Gene: PP2C-beta|PP2C-beta-X|PP2CB|PP2CBETA|PPC2BETAX

Gene Summary: The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences.

Gene is located in Chromosome: 2

Location in Chromosome : 2p21

Description of this Gene: protein phosphatase, Mg2+/Mn2+ dependent 1B

Type of Gene: protein-coding