Gene: PRCC

Alternate names for this Gene: RCCP1|TPRC

Gene Summary: This gene encodes a protein that may play a role in pre-mRNA splicing. Chromosomal translocations (X;1)(p11;q21) that result in fusion of this gene to TFE3 (GeneID 7030) have been associated with papillary renal cell carcinoma. A PRCC-TFE3 fusion protein is expressed in affected carcinomas and is likely associated with altered gene transactivation. This fusion protein has also been associated with disruption of the cell cycle.

Gene is located in Chromosome: 1

Location in Chromosome : 1q23.1

Description of this Gene: proline rich mitotic checkpoint control factor

Type of Gene: protein-coding

rs9330272 in PRCC gene and Body Height PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.