Gene: PRKAR1B

Alternate names for this Gene: PRKAR1

Gene Summary: The protein encoded by this gene is a regulatory subunit of cyclic AMP-dependent protein kinase A (PKA), which is involved in the signaling pathway of the second messenger cAMP. Two regulatory and two catalytic subunits form the PKA holoenzyme, disbands after cAMP binding. The holoenzyme is involved in many cellular events, including ion transport, metabolism, and transcription. Several transcript variants encoding the same protein have been found for this gene.

Gene is located in Chromosome: 7

Location in Chromosome : 7p22.3

Description of this Gene: protein kinase cAMP-dependent type I regulatory subunit beta

Type of Gene: protein-coding

rs75444260 in PRKAR1B gene and Amino acids measurement PMID 30659259 2019 Genetic basis for plasma amino acid concentrations based on absolute quantification: a genome-wide association study in the Japanese population.

rs9330360 in PRKAR1B gene and Body Height PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs35750745 in PRKAR1B gene and Hematocrit procedure PMID 27863252 2016 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.

rs35750745 in PRKAR1B gene and Hemoglobin measurement PMID 27863252 2016 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.

rs75444260 in PRKAR1B gene and Histidine measurement PMID 30659259 2019 Genetic basis for plasma amino acid concentrations based on absolute quantification: a genome-wide association study in the Japanese population.

rs71016890 in PRKAR1B gene and Red Blood Cell Count measurement PMID 27863252 2016 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.

rs75444260 in PRKAR1B gene and Tryptophan measurement PMID 30659259 2019 Genetic basis for plasma amino acid concentrations based on absolute quantification: a genome-wide association study in the Japanese population.

rs9719461 in PRKAR1B gene and Varicosity PMID 30566020 2018 Clinical and Genetic Determinants of Varicose Veins.