Gene: PTGER4

Alternate names for this Gene: EP4|EP4R

Gene Summary: The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses.

Gene is located in Chromosome: 5

Location in Chromosome : 5p13.1

Description of this Gene: prostaglandin E receptor 4

Type of Gene: protein-coding

Gene: TTC33

Alternate names for this Gene: OSRF

Gene Summary:

Gene is located in Chromosome: 5

Location in Chromosome : 5p13.1

Description of this Gene: tetratricopeptide repeat domain 33

Type of Gene: protein-coding