Gene: RALA
Alternate names for this Gene: RAL
Gene Summary: The product of this gene belongs to the small GTPase superfamily, Ras family of proteins. GTP-binding proteins mediate the transmembrane signaling initiated by the occupancy of certain cell surface receptors. This gene encodes a low molecular mass ras-like GTP-binding protein that shares about 50% similarity with other ras proteins.
Gene is located in Chromosome: 7
Location in Chromosome : 7p14.1
Description of this Gene: RAS like proto-oncogene A
Type of Gene: protein-coding
rs1554297905 in
RALA gene and
Autistic behavior
PMID 30500825 2018 De novo mutations in the GTP/GDP-binding region of RALA, a RAS-like small GTPase, cause intellectual disability and developmental delay.
rs1554297905 in
RALA gene and
Clinodactyly of the 5th finger
PMID 30500825 2018 De novo mutations in the GTP/GDP-binding region of RALA, a RAS-like small GTPase, cause intellectual disability and developmental delay.
rs1554297905 in
RALA gene and
Dysmorphic facies
PMID 30500825 2018 De novo mutations in the GTP/GDP-binding region of RALA, a RAS-like small GTPase, cause intellectual disability and developmental delay.
rs1554297905 in
RALA gene and
Microcephaly (physical finding)
PMID 30500825 2018 De novo mutations in the GTP/GDP-binding region of RALA, a RAS-like small GTPase, cause intellectual disability and developmental delay.
rs1554297905 in
RALA gene and
Moderate intellectual disability
PMID 30500825 2018 De novo mutations in the GTP/GDP-binding region of RALA, a RAS-like small GTPase, cause intellectual disability and developmental delay.
rs1554297905 in
RALA gene and
Speech impairment
PMID 30500825 2018 De novo mutations in the GTP/GDP-binding region of RALA, a RAS-like small GTPase, cause intellectual disability and developmental delay.