Gene: RGS5

Alternate names for this Gene: MST092|MST106|MST129|MSTP032|MSTP092|MSTP106|MSTP129

Gene Summary: This gene encodes a member of the regulators of G protein signaling (RGS) family. The RGS proteins are signal transduction molecules which are involved in the regulation of heterotrimeric G proteins by acting as GTPase activators. This gene is a hypoxia-inducible factor-1 dependent, hypoxia-induced gene which is involved in the induction of endothelial apoptosis. This gene is also one of three genes on chromosome 1q contributing to elevated blood pressure. Alternatively spliced transcript variants have been identified.

Gene is located in Chromosome: 1

Location in Chromosome : 1q23.3

Description of this Gene: regulator of G protein signaling 5

Type of Gene: protein-coding

Gene: NUF2

Alternate names for this Gene: CDCA1|CT106|NUF2R

Gene Summary: This gene encodes a protein that is highly similar to yeast Nuf2, a component of a conserved protein complex associated with the centromere. Yeast Nuf2 disappears from the centromere during meiotic prophase when centromeres lose their connection to the spindle pole body, and plays a regulatory role in chromosome segregation. The encoded protein is found to be associated with centromeres of mitotic HeLa cells, which suggests that this protein is a functional homolog of yeast Nuf2. Alternatively spliced transcript variants that encode the same protein have been described.

Gene is located in Chromosome: 1

Location in Chromosome : 1q23.3

Description of this Gene: NUF2 component of NDC80 kinetochore complex

Type of Gene: protein-coding