Gene: RUVBL2

Alternate names for this Gene: CGI-46|ECP-51|ECP51|INO80J|REPTIN|RVB2|TAP54-beta|TIH2|TIP48|TIP49B

Gene Summary: This gene encodes the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair. Functional analysis showed that this gene product has both ATPase and DNA helicase activities. This gene is physically linked to the CGB/LHB gene cluster on chromosome 19q13.3, and is very close (55 nt) to the LHB gene, in the opposite orientation.

Gene is located in Chromosome: 19

Location in Chromosome : 19q13.33

Description of this Gene: RuvB like AAA ATPase 2

Type of Gene: protein-coding

rs139643250 in RUVBL2 gene and Blood Protein Measurement PMID 29875488 2018 Genomic atlas of the human plasma proteome.

PMID 30072576 2018 Co-regulatory networks of human serum proteins link genetics to disease.

rs753307 in RUVBL2 gene and Human chorionic gonadotropin measurement PMID 28240269 2017 Connecting genetic risk to disease end points through the human blood plasma proteome.