Gene: SAT2

Alternate names for this Gene: SSAT-2|SSAT2

Gene Summary:

Gene is located in Chromosome: 17

Location in Chromosome : 17p13.1

Description of this Gene: spermidine/spermine N1-acetyltransferase family member 2

Type of Gene: protein-coding

Gene: SHBG

Alternate names for this Gene: ABP|SBP|TEBG

Gene Summary: This gene encodes a steroid binding protein that was first described as a plasma protein secreted by the liver but is now thought to participate in the regulation of steroid responses. The encoded protein transports androgens and estrogens in the blood, binding each steroid molecule as a dimer formed from identical or nearly identical monomers. Polymorphisms in this gene have been associated with polycystic ovary syndrome and type 2 diabetes mellitus. Alternative splicing results in multiple transcript variants.

Gene is located in Chromosome: 17

Location in Chromosome : 17p13.1

Description of this Gene: sex hormone binding globulin

Type of Gene: protein-coding

rs858519 in SAT2;SHBG gene and Blood Protein Measurement PMID 30072576 2018 Co-regulatory networks of human serum proteins link genetics to disease.

rs858519 in SAT2;SHBG gene and Waist-Hip Ratio PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.