Gene: SCEL

Alternate names for this Gene: -

Gene Summary: The protein encoded by this gene is a precursor to the cornified envelope of terminally differentiated keratinocytes. This protein localizes to the periphery of cells and may function in the assembly or regulation of proteins in the cornified envelope. Transcript variants encoding different isoforms exist. A transcript variant utilizing an alternative polyA signal has been described in the literature, but its full-length nature has not been determined.

Gene is located in Chromosome: 13

Location in Chromosome : 13q22.3

Description of this Gene: sciellin

Type of Gene: protein-coding

rs73229101 in SCEL gene and Waist-Hip Ratio PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.