Gene: SCUBE1

Alternate names for this Gene: -

Gene Summary: This gene encodes a cell surface glycoprotein that is a member of the SCUBE (signal peptide, CUB domain, EGF (epidermal growth factor)-like protein) family. Family members have an amino-terminal signal peptide, nine copies of EGF-like repeats and a CUB domain at the carboxyl terminus. This protein is expressed in platelets and endothelial cells and may play an important role in vascular biology.

Gene is located in Chromosome: 22

Location in Chromosome : 22q13.2

Description of this Gene: signal peptide, CUB domain and EGF like domain containing 1

Type of Gene: protein-coding

rs2744874 in SCUBE1 gene and Blood Protein Measurement PMID 30072576 2018 Co-regulatory networks of human serum proteins link genetics to disease.

rs139030 in SCUBE1 gene and Body Height PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs528981060 in SCUBE1 gene and Degenerative polyarthritis PMID 30664745 2019 Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data.