Gene: SDK1

Alternate names for this Gene: -

Gene Summary: The protein encoded by this gene is a member of the immunoglobulin superfamily. The protein contains six immunoglobulin-like domains and thirteen fibronectin type III domains. Fibronectin type III domains are present in both extracellular and intracellular proteins and tandem repeats are known to contain binding sites for DNA, heparin and the cell surface. Alternative splicing results in multiple transcript variants.

Gene is located in Chromosome: 7

Location in Chromosome : 7p22.2

Description of this Gene: sidekick cell adhesion molecule 1

Type of Gene: protein-coding

rs6462203 in SDK1 gene and Anxiety Disorders PMID 31116379 2019 Genetic Variants Associated With Anxiety and Stress-Related Disorders: A Genome-Wide Association Study and Mouse-Model Study.

rs17134117 in SDK1 gene and Autistic Disorder PMID 22935194 2013 A genome-wide association study of autism incorporating autism diagnostic interview-revised, autism diagnostic observation schedule, and social responsiveness scale.

rs10085617 in SDK1 gene and Cannabis use PMID 30150663 2018 GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal influence of schizophrenia.

rs117749317 in SDK1 gene and Cardiac troponin T measurement PMID 31014085 2019 Cardiac Troponin T and Troponin I in the General Population.

rs10242223 in SDK1 gene and Gastroesophageal reflux disease PMID 31527586 2019 Gastroesophageal reflux GWAS identifies risk loci that also associate with subsequent severe esophageal diseases.

rs34912216 in SDK1 gene and Motion Sickness PMID 25628336 2015 Genetic variants associated with motion sickness point to roles for inner ear development, neurological processes and glucose homeostasis.

rs10226621 in SDK1 gene and Narcolepsy PMID 19629137 2009 Genome-wide association database developed in the Japanese Integrated Database Project.

rs10234405 in SDK1 gene and Primary biliary cirrhosis PMID 23000144 2012 Genome-wide association study identifies TNFSF15 and POU2AF1 as susceptibility loci for primary biliary cirrhosis in the Japanese population.

rs1108879 in SDK1 gene and Smoking PMID 30643258 2019 Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.

rs6462411 in SDK1 gene and Thyroid stimulating hormone measurement PMID 19197348 2009 Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae.

rs6462411 in SDK1 gene and Triglycerides measurement PMID 19197348 2009 Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae.

rs1019914 in SDK1 gene and mathematical ability PMID 30038396 2018 Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.