Gene: SEC11A

Alternate names for this Gene: 1810012E07Rik|SEC11L1|SPC18|SPCS4A|sid2895

Gene Summary: This gene encodes a member of the peptidase S26B family. The encoded protein is an 18kDa subunit of the signal peptidase complex and has been linked to cell migration and invasion, gastric cancer and lymph node metastasis. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 8.

Gene is located in Chromosome: 15

Location in Chromosome : 15q25.2-q25.3

Description of this Gene: SEC11 homolog A, signal peptidase complex subunit

Type of Gene: protein-coding

rs55945116 in SEC11A gene and Bipolar Disorder PMID 30552317 2018 Exploratory genome-wide association analysis of response to ketamine and a polygenic analysis of response to scopolamine in depression.

rs12912342 in SEC11A gene and Blood Protein Measurement PMID 30072576 2018 Co-regulatory networks of human serum proteins link genetics to disease.

rs55945116 in SEC11A gene and Major Depressive Disorder PMID 30552317 2018 Exploratory genome-wide association analysis of response to ketamine and a polygenic analysis of response to scopolamine in depression.

rs12440825 in SEC11A gene and Smoking PMID 26053186 2015 Mercapturic Acids Derived from the Toxicants Acrolein and Crotonaldehyde in the Urine of Cigarette Smokers from Five Ethnic Groups with Differing Risks for Lung Cancer.

rs12440825 in SEC11A gene and Smoking Behaviors PMID 26053186 2015 Mercapturic Acids Derived from the Toxicants Acrolein and Crotonaldehyde in the Urine of Cigarette Smokers from Five Ethnic Groups with Differing Risks for Lung Cancer.

rs55945116 in SEC11A gene and Unipolar Depression PMID 30552317 2018 Exploratory genome-wide association analysis of response to ketamine and a polygenic analysis of response to scopolamine in depression.

rs55945116 in SEC11A gene and response to ketamine PMID 30552317 2018 Exploratory genome-wide association analysis of response to ketamine and a polygenic analysis of response to scopolamine in depression.