Gene: SEMA3E
Alternate names for this Gene: M-SEMAH|M-SemaK|SEMAH|coll-5
Gene Summary: Semaphorins are a large family of conserved secreted and membrane associated proteins which possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Based on sequence and structural similarities, semaphorins are put into eight classes: invertebrates contain classes 1 and 2, viruses have class V, and vertebrates contain classes 3-7. Semaphorins serve as axon guidance ligands via multimeric receptor complexes, some (if not all) containing plexin proteins. This gene encodes a class 4 semaphorin. This gene encodes a class 3 semaphorin. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene is located in Chromosome: 7
Location in Chromosome : 7q21.11
Description of this Gene: semaphorin 3E
Type of Gene: protein-coding