Gene: SERPINB13

Alternate names for this Gene: HSHUR7SEQ|HUR7|PI13|headpin

Gene Summary: The protein encoded by this gene is a member of the serpin family of serine protease inhibitors. The encoded protein inhibits the activity of cathepsin K and is itself transcriptionally repressed by RUNX1. This gene is downregulated in many types of cancer.

Gene is located in Chromosome: 18

Location in Chromosome : 18q21.33

Description of this Gene: serpin family B member 13

Type of Gene: protein-coding

rs12968338 in SERPINB13 gene and Blood basophil count (lab test) PMID 27863252 2016 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.

rs12968338 in SERPINB13 gene and Eosinophil count procedure PMID 27863252 2016 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.

PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.