Gene: SLC25A12

Alternate names for this Gene: AGC1|ARALAR|DEE39|EIEE39

Gene Summary: This gene encodes a calcium-binding mitochondrial carrier protein. The encoded protein localizes to the mitochondria and is involved in the exchange of aspartate for glutamate across the inner mitochondrial membrane. Polymorphisms in this gene may be associated with autism, and mutations in this gene may also be a cause of global cerebral hypomyelination. Alternatively spliced transcript variants have been observed for this gene.

Gene is located in Chromosome: 2

Location in Chromosome : 2q31.1

Description of this Gene: solute carrier family 25 member 12

Type of Gene: protein-coding

Gene: HAT1

Alternate names for this Gene: KAT1

Gene Summary: The protein encoded by this gene is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5. Alternatively spliced transcript variants have been identified for this gene.

Gene is located in Chromosome: 2

Location in Chromosome : 2q31.1

Description of this Gene: histone acetyltransferase 1

Type of Gene: protein-coding